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| | 1. |
2009 Apr |
Comparative analysis of chemical compositions and antimicrobial activities of essential oils from Abies holophylla and Abies koreana activities of essential oils from Abies holophylla and Abies koreana.
Lee JH, Hong SK
J. Microbiol. Biotechnol. 2009 Apr;19(4):372-7.
Abstract
The chemical compositions and antibacterial and antifungal activities of essential oils extracted from Abies holophylla and A. koreana were investigated. GC-MS analysis revealed that 38 compounds comprised 95.88% of the A. holophylla essential oil, with the main components being bicyclo[2.2.1]heptan-2-ol (28.05%), delta3-carene (13.85%), alpha-pinene (11.68%), camphene (10.41%), dl-limonene (7.61%), beta-myrcene (7.11%), trans-caryophyllene (5.36%), and alpha- bisabolol (3.67%). In the essential oil from A. koreana, 36 compounds comprised 98.67% of the oil, and the main compounds were bornyl ester (41.79%), camphene (15.31%), alpha-pinene (11.19%), dl-limonene (8.58%), fenchyl acetate (5.55%), and alpha-terpinene (2.29%). Both essential oils showed great potential of antibacterial activity against several bacteria tested, in the range of 2.2-8.8 mug per disc by the agar disc diffusion method, and minimal inhibitory concentration (MIC) values of 5.5-21.8 mg/ml by the microdilution method. Both oils showed very effective antifungal activities toward all pathogenic strains tested, including Candida glabrata, with MIC values in the range of 0.5-2.2 mg/ml. As a whole, A.koreanaoil showed better antibacterial and antifungal properties than A.holophylla oil.
[Pubmed: 19420993]
| | 2. |
2010 Mar 6 |
Autotrophic and heterotrophic respiration in needle fir and Quercus-dominated stands in a cool-temperate forest, central Korea.
Lee NY, Koo JW, Noh NJ, Kim J, Son Y
J Plant Res. 2010 Mar 6; [Epub ahead of print]
Abstract
To investigate annual variation in soil respiration (R (S)) and its components [autotrophic (R (A)) and heterotrophic (R (H))] in relation to seasonal changes in soil temperature (ST) and soil water content (SWC) in an Abies holophylla stand (stand A) and a Quercus-dominated stand (stand Q), we set up trenched plots and measured R (S), ST and SWC for 2 years. The mean annual rate of R (S) was 436 mg CO(2) m(-2) h(-1), ranging from 76 to 1,170 mg CO(2) m(-2) h(-1), in stand A and 376 mg CO(2) m(-2) h(-1), ranging from 82 to 1,133 mg CO(2) m(-2) h(-1), in stand Q. A significant relationship between R (S) and its components and ST was observed over the 2 years in both stands, whereas a significant correlation between R (A) and SWC was detected only in stand Q. On average over the 2 years, R (A) accounted for approximately 34% (range 17-67%) and 31% (15-82%) of the variation in R (S) in stands A and Q, respectively. Our results suggested that vegetation type did not significantly affect the annual mean contributions of R (A) or R (H), but did affect the pattern of seasonal change in the contribution of R (A) to R (S).
[Pubmed: 20204671]
| | 3. |
2010 Sep 26 |
The Use of Endophytes to Obtain Bioactive Compounds and Their Application in Biotransformation Process
Pimentel, Molina, Dionísio, Maróstica Junior, Pastore
Biotechnol Res Int 2010 Sep 26;2011. published online before print
Abstract
Endophytes are microorganisms that reside asymptomatically in the tissues of higher plants and are a promising source of novel organic natural metabolites exhibiting a variety of biological activities. The laboratory of Bioaromas (Unicamp, Brazil) develops research in biotransformation processes and functional evaluation of natural products. With the intent to provide subsidies for studies on endophytic microbes related to areas cited before, this paper focuses particularly on the role of endophytes on the production of anticancer, antimicrobial, and antioxidant compounds and includes examples that illustrate their potential for human use. It also describes biotransformation as an auspicious method to obtain novel bioactive compounds from microbes. Biotransformation allows the production of regio- and stereoselective compounds under mild conditions that can be labeled as “natural,” as discussed in this paper.
[Pubmed: 21350663]
| | 4. |
2011 Dec 12 |
Sesquiterpenoids and triterpenoids from Abies holophylla and their bioactivities.
Xia JH, Zhang SD, Li YL, Wu L, Zhu ZJ, Yang XW, Zeng HW, Li HL, Wang N, Steinmetz A, Zhang WD
Phytochemistry. 2012 Feb;74:178-84. Epub 2011 Dec 12.
Abstract
Six previously unreported and 11 known terpenoids were isolated from Abies holophylla. The structures of the six compounds were established as two unusual bisabolane sesquiterpenoids, three nortriterpenoids, and one 3,4-seco-triterpenoid based on the detailed analysis of their 1D and 2D NMR spectroscopic data. In addition, electronic circular dichroism (ECD) calculations and molecular orbital (MO) analysis were used to assign the absolute configuration of one bisabolane sesquiterpenoid, abiesesquine A. Abiesesquine A showed the strongest inhibitory effects against LPS-induced nitric oxide (NO) production in RAW264.7 macrophages with an IC(50) value of 113.1 μM. Lanosta-7,9(11),24-trien-26-oic acid showed potent cytotoxic activity against COLO-205, LOVO, and QGY-7703 tumor cells with IC(50) values of 0.9, 4.2, and 2.0 μM, respectively. (23R,25R)-3,4-seco-9βH-Lanosta-4(28),7-dien-26,23-olid-3-oic acid, exhibited a significant antiproliferation effect against A549 cells (IC(50)=14.7 μM).
[Pubmed: 22169016]
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